diff --git a/.ci/azure/windows.yml b/.ci/azure/windows.yml
index 30257601a80..90073808dca 100644
--- a/.ci/azure/windows.yml
+++ b/.ci/azure/windows.yml
@@ -149,7 +149,7 @@ jobs:
     # Add for gtest-parallel, it hangs now (CVS-33386)
     #python $(BUILD_DIR)\gtest-parallel\gtest-parallel $(BIN_DIR)\MklDnnFunctionalTests --workers=$(WORKERS_NUMBER) --dump_json_test_results=MklDnnFunctionalTests.json --gtest_filter=*smoke* -- --gtest_print_time=1
   - script: |
-      set PATH=$(REPO_DIR)\inference-engine\temp\tbb\bin;$(REPO_DIR)\inference-engine\temp\opencv_4.5.0\opencv\bin;%PATH%
+      set PATH=$(REPO_DIR)\inference-engine\temp\tbb\bin;$(REPO_DIR)\inference-engine\temp\opencv_4.5.1\opencv\bin;%PATH%
       set DATA_PATH=$(BUILD_DIR)\testdata
       set MODELS_PATH=$(BUILD_DIR)\testdata
       $(BIN_DIR)\MklDnnFunctionalTests --gtest_filter=*smoke* --gtest_print_time=1 --gtest_output=xml:TEST-MklDnnFunctionalTests.xml
@@ -157,7 +157,7 @@ jobs:
     continueOnError: false
 
   - script: |
-      set PATH=$(REPO_DIR)\inference-engine\temp\tbb\bin;$(REPO_DIR)\inference-engine\temp\opencv_4.5.0\opencv\bin;%PATH%
+      set PATH=$(REPO_DIR)\inference-engine\temp\tbb\bin;$(REPO_DIR)\inference-engine\temp\opencv_4.5.1\opencv\bin;%PATH%
       set DATA_PATH=$(BUILD_DIR)\testdata
       set MODELS_PATH=$(BUILD_DIR)\testdata
       $(BIN_DIR)\InferenceEngineCAPITests --gtest_output=xml:TEST-InferenceEngineCAPITests.xml
diff --git a/inference-engine/cmake/dependencies.cmake b/inference-engine/cmake/dependencies.cmake
index e4d4327d155..419c0f369bb 100644
--- a/inference-engine/cmake/dependencies.cmake
+++ b/inference-engine/cmake/dependencies.cmake
@@ -181,8 +181,8 @@ endif ()
 if (ENABLE_OPENCV)
     reset_deps_cache(OpenCV_DIR)
 
-    set(OPENCV_VERSION "4.5.0")
-    set(OPENCV_BUILD "36")
+    set(OPENCV_VERSION "4.5.1")
+    set(OPENCV_BUILD "044")
     set(OPENCV_BUILD_YOCTO "337")
 
     if (AARCH64)