diff --git a/cmake/features.cmake b/cmake/features.cmake
index 6de4f9d962d..4687016191a 100644
--- a/cmake/features.cmake
+++ b/cmake/features.cmake
@@ -177,7 +177,7 @@ ov_dependent_option (ENABLE_SYSTEM_SNAPPY "Enables use of system version of Snap
 ov_dependent_option (ENABLE_PYTHON_PACKAGING "Enables packaging of Python API in APT / YUM" OFF
     "ENABLE_PYTHON;UNIX" OFF)
 
-ov_dependent_option(ENABLE_JS "Enables JS API building" ON "NOT ANDROID" OFF)
+ov_dependent_option(ENABLE_JS "Enables JS API building" ON "NOT ANDROID;NOT EMSCRIPTEN" OFF)
 
 ov_option(ENABLE_OPENVINO_DEBUG "Enable output for OPENVINO_DEBUG statements" OFF)