diff --git a/dubbo-config/dubbo-config-spring/src/main/java/org/apache/dubbo/config/spring/context/DubboInfraBeanRegisterPostProcessor.java b/dubbo-config/dubbo-config-spring/src/main/java/org/apache/dubbo/config/spring/context/DubboInfraBeanRegisterPostProcessor.java
index 2f700127a2..d9f4f2b2ce 100644
--- a/dubbo-config/dubbo-config-spring/src/main/java/org/apache/dubbo/config/spring/context/DubboInfraBeanRegisterPostProcessor.java
+++ b/dubbo-config/dubbo-config-spring/src/main/java/org/apache/dubbo/config/spring/context/DubboInfraBeanRegisterPostProcessor.java
@@ -89,6 +89,11 @@ public class DubboInfraBeanRegisterPostProcessor implements BeanDefinitionRegist
 
         // register ConfigManager singleton
         beanFactory.registerSingleton(ConfigManager.BEAN_NAME, applicationModel.getApplicationConfigManager());
+
+        // fix https://github.com/apache/dubbo/issues/10278
+        if (registry != null){
+            registry.removeBeanDefinition(BEAN_NAME);
+        }
     }
 
     @Override