diff --git a/.jenkins/Jenkinsfile b/.jenkins/Jenkinsfile
index e9198a4cdd..3809eecafd 100644
--- a/.jenkins/Jenkinsfile
+++ b/.jenkins/Jenkinsfile
@@ -254,7 +254,7 @@ def tasks() {
     (isStageEnabled(axis['step'])) && // skip disabled steps
     !(axis['python'] != pythonDefault && 'cqlsh-test' != axis['step']) && // Use only python 3.8 for all tests but cqlsh-test
     !(axis['cython'] != 'no' && 'cqlsh-test' != axis['step']) && // cython only for cqlsh-test, disable for others
-    !(axis['cython'] == 'yes' && (axis['python'] == '3.12' || axis['python'] == '3.13')) && // Skip cython for Python 3.12+
+    !(axis['cython'] == 'yes' && (axis['python'] == '3.12' || axis['python'] == '3.13')) && // Skip cython for Python 3.12+ see CASSANDRA-21482
     !(axis['jdk'] != javaVersionDefault && ('cqlsh-test' == axis['step'] || 'simulator-dtest' == axis['step'] || axis['step'].contains('dtest-upgrade'))) && // run cqlsh-test, simulator-dtest, *dtest-upgrade only with jdk11
     // Disable splits for all but proper stages
     !(axis['split'] > 1 && !stepsMap.findAll { entry -> entry.value.splits >= axis['split'] }.keySet().contains(axis['step'])) &&