diff --git a/CHANGES.txt b/CHANGES.txt
index b1b3788dc4..ba7c5a1be4 100644
--- a/CHANGES.txt
+++ b/CHANGES.txt
@@ -1,4 +1,5 @@
 4.2
+ * Change shebangs of Python scripts to resolve Python 3 from env command (CASSANDRA-17832)
  * Add reasons to guardrail messages and consider guardrails in the error message for needed ALLOW FILTERING (CASSANDRA-17967)
  * Add support for CQL functions on collections, tuples and UDTs (CASSANDRA-17811)
  * Add flag to exclude nodes from local DC when running nodetool rebuild (CASSANDRA-17870)
diff --git a/bin/cqlsh.py b/bin/cqlsh.py
index 2d079c0fe1..0b0ee39610 100755
--- a/bin/cqlsh.py
+++ b/bin/cqlsh.py
@@ -1,4 +1,4 @@
-#!/usr/bin/python3
+#!/usr/bin/env python3
 
 # Licensed to the Apache Software Foundation (ASF) under one
 # or more contributor license agreements.  See the NOTICE file
diff --git a/pylib/setup.py b/pylib/setup.py
index a9f654a677..f5fd1841b3 100755
--- a/pylib/setup.py
+++ b/pylib/setup.py
@@ -1,4 +1,4 @@
-#!/usr/bin/python
+#!/usr/bin/env python3
 # Licensed to the Apache Software Foundation (ASF) under one
 # or more contributor license agreements.  See the NOTICE file
 # distributed with this work for additional information
diff --git a/redhat/cassandra.spec b/redhat/cassandra.spec
index 3711dfd85d..5004eed585 100644
--- a/redhat/cassandra.spec
+++ b/redhat/cassandra.spec
@@ -17,8 +17,8 @@
 #
 
 %define __jar_repack %{nil}
-# Turn off the brp-python-bytecompile script
-%global __os_install_post %(echo '%{__os_install_post}' | sed -e 's!/usr/lib[^[:space:]]*/brp-python-bytecompile[[:space:]].*$!!g')
+# Turn off the brp-python-bytecompile script and mangling shebangs for Python scripts
+%global __os_install_post %(echo '%{__os_install_post}' | sed -e 's!/usr/lib[^[:space:]]*/brp-python-bytecompile[[:space:]].*$!!g' -e 's!/usr/lib[^[:space:]]*/brp-mangle-shebangs[[:space:]].*$!!g')
 
 # rpmbuild should not barf when it spots we ship
 # binary executable files in our 'noarch' package
diff --git a/redhat/noboolean/cassandra.spec b/redhat/noboolean/cassandra.spec
index 8c04fdb4cf..cc3d630346 100644
--- a/redhat/noboolean/cassandra.spec
+++ b/redhat/noboolean/cassandra.spec
@@ -17,8 +17,8 @@
 #
 
 %define __jar_repack %{nil}
-# Turn off the brp-python-bytecompile script
-%global __os_install_post %(echo '%{__os_install_post}' | sed -e 's!/usr/lib[^[:space:]]*/brp-python-bytecompile[[:space:]].*$!!g')
+# Turn off the brp-python-bytecompile script and mangling shebangs for Python scripts
+%global __os_install_post %(echo '%{__os_install_post}' | sed -e 's!/usr/lib[^[:space:]]*/brp-python-bytecompile[[:space:]].*$!!g' -e 's!/usr/lib[^[:space:]]*/brp-mangle-shebangs[[:space:]].*$!!g')
 
 # rpmbuild should not barf when it spots we ship
 # binary executable files in our 'noarch' package